m-PEG4-CH2COOH 是一种基于 PEG 的 PROTAC linker，用于 PROTAC 合成。
货号:ajcx37200
CAS:16024-66-1
分子式:C11H22O7
分子量：266.29
溶解度:DMSO : 100 mg/mL (375.53 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

m-PEG4-CH2COOH is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[1]. TaoDeng, et al. Monodisperse oligoethylene glycols modified Propofol prodrugs. Bioorganic & Medicinal Chemistry Letters.