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19R(20S)-EpDPA
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
19R(20S)-EpDPA图片
规格:98%
分子量:344.5
包装与价格:
包装价格(元)
25ug电议
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500ug电议

产品介绍
A DHA metabolite
货号:ajcx21168
CAS:2242542-60-3
分子式:C22H32O3
分子量:344.5
溶解度:Ethanol: soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:

19R(20S)-EpDPA is an oxylipin and a metabolite of docosahexaenoic acid .1,2It is formed from DHA by various cytochrome P450 (CYP) isoforms in a stereoselective manner.219R(20S)-EpDPA (30 nM) prevents calcium-induced increases in the spontaneous beating of isolated neonatal rat cardiomyocytes (NRCMs).3


1.Cinelli, M.A., Yang, J., Scharmen, A., et al.Enzymatic synthesis and chemical inversion provide both enantiomers of bioactive epoxydocosapentaenoic acidsJ. Lipid Res.59(11)2237-2252(2018) 2.Lucas, D., Goulitquer, S., Marienhagen, J., et al.Stereoselective epoxidation of the last double bond of polyunsaturated fatty acids by human cytochromes P450J. Lipid Res.51(5)1125-1133(2010) 3.Burke, J.E., and Dennis, E.A.Phospholipase A2 structure/function, mechanism, and signalingJ. Lipid Res.50(Suppl)S237-S242(2009)