Potent apelin agonist; bioactive fragment of ELA-32
货号:ajcx27510
CAS:1886973-05-2
分子式:C75H119N25O17S2
分子量：1707.03
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Potent apelin (APJ) receptor agonist (Ki = 0.93 nM). Bioactive fragment of ELA-32 . Activates Gαi1 pathway and β-arrestin-2 recruitment. Reduces arterial pressure in rat hearts. Active in vivo. ELA-14 negative control (Cat.No. 6294) also available.

Murza et al (2016) Discovery and structure-activity relationship of a bioactive fragment of ELABELA that modulates vascular and cardiac functions. J.Med.Chem. 59 2962 PMID:26986036