Ro 04-6790 is a potent and selective 5-HT6 receptor antagonist (pKis are 7.26 and 7.35 at rat and human 5-HT6 receptors respectively). Ro 04-6790 exhibits no affinity at a range of other receptors (IC50 > 10 μM). References: Thur KE, Nelson AJ, Cassaday HJ. Ro 04-6790-induced cognitive enhancement: no effect in trace conditioning and novel object recognition procedures in adult male Wistar rats. Pharmacol Biochem Behav. 2014 Dec;127:42-8. doi: 10.1016/j.pbb.2014.10.006. Epub 2014 Oct 24. PubMed PMID: 25450117; PubMed Central PMCID: PMC4258611.
纯度:≥98%
CAS:202466-68-0