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死亡结构域接头蛋白DENN抗体
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
Anti-MADD
Anti-MAP kinase activating death domain Antibody
产品介绍
靶标:

MADD


产品别名:

DEEAH; DENN; IG20; NEDDISH; RAB3GEP; RabGEF; MADD; MAP kinase activating death domain; MAP kinase activating death domain; MAP kinase-activating death domain protein; Rab3 GDP/GTP exchange factor; differentially expressed in normal and neoplastic cells; insulinoma glucagonoma clone 20; rab3 GDP/GTP exchange protein; 死亡结构域接头蛋白DENN;


背景信息:
Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],

宿主:Rbt
类型:Pab
同种型:IgG  
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user           
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。