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髓易位基因相关蛋白1抗体
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称
Anti-CBFA2T2
Anti-CBFA2/RUNX1 partner transcriptional co-repressor 2 Antibody
产品介绍
靶标：

CBFA2T2


产品别名：

EHT； MTGR1； ZMYND3； p85； CBFA2T2； CBFA2/RUNX1 partner transcriptional co-repressor 2； CBFA2/RUNX1 partner transcriptional co-repressor 2； protein CBFA2T2； CBFA2/RUNX1 translocation partner 2； ETO homolog on chromosome 20； ETO homologous on chromosome 20； MTG8-like protein； MTG8-related protein 1； core-binding factor, runt domain, alpha subunit 2; translocated to, 2； myeloid translocation gene-related protein 1； myeloid translocation-related protein 1； 髓易位基因相关蛋白1；


背景信息：
In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described.

宿主：Rbt
类型：Pab
同种型:IgG  
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user           
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。