LEI-106 is a potent sn-1 DAGLalpha inhibitor, blocking the hydrolysis of sn-1-oleoyl-2-AG, inhibiting the hydrolysis of 2-AG by the monoacylglycerol lipase ABHD6. References: Janssen FJ, Deng H, Baggelaar MP, Allarà M, van der Wel T, den Dulk H, Ligresti A, van Esbroeck AC, McGuire R, Di Marzo V, Overkleeft HS, van der Stelt M. Discovery of glycine sulfonamides as dual inhibitors of sn-1-diacylglycerol lipase α and α/β-hydrolase domain 6. J Med Chem. 2014 Aug 14;57(15):6610-22. doi: 10.1021/jm500681z. Epub 2014 Jul 23. PubMed PMID: 24988361.

纯度：≥98%

CAS：1620582-23-1