Roslin 2 is a p53 reactivator that disrupts the FAK and p53 interaction, and reactivates transcriptional activity of p53 with p21, Mdm-2 and Bax transcriptional targets. Roslin 2 decreases viability and clonogenicity of cancer cells, and inhibits tumor growth. References: Learmount J, Callaby R, Taylor M. An observational study of ewe treatments at lambing on early infection in lambs on UK sheep farms. Vet Parasitol. 2018 Apr 15;253:55-59. doi: 10.1016/j.vetpar.2018.02.026. Epub 2018 Feb 12. PubMed PMID: 29605004.
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CAS:29574-21-8