LC-SPDP Crosslinker, formerly known as SPDP-C6-NHS ester, is a cleavable, water insoluble, amino and thiol (sulfhydryl) reactive heterobifunctional crosslinking reagent. The "long chain" LC-SPDP crosslinking reagent has a 15.7 angstrom spacer arm, compared to the shorter 6.8 angstrom spacer arm version of SPDP crosslinker. Often, due to steric hindrances, it is desirable to empirically test which of the two versions will work best in your specific application. LC-SPDP Crosslinker is useful for making Antibody Drug Conjugates (ADCs). References: Woo BH, Lee JT, Lee KC. Ricin A immunotoxins of IgG and Fab of anti-CALLA monoclonal antibody: effect of water soluble long-chain SPDP on conjugate yield, immunoselectivity and cytotoxicity. Arch Pharm Res. 1994 Dec;17(6):452-7. PubMed PMID: 10319157.

纯度：≥98%

CAS：158913-22-5