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G蛋白偶联受体ARHGEF18抗体
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称
Anti-ARHGEF18
Anti-Rho/Rac guanine nucleotide exchange factor 18 Antibody
产品介绍
靶标：

ARHGEF18


产品别名：

P114-RhoGEF； RP78； SA-RhoGEF； p114RhoGEF； ARHGEF18； Rho/Rac guanine nucleotide exchange factor 18； Rho/Rac guanine nucleotide exchange factor 18； rho guanine nucleotide exchange factor 18； 114 kDa Rho-specific guanine nucleotide exchange factor； Rho-specific guanine nucleotide exchange factor p114； Rho/Rac guanine nucleotide exchange factor (GEF) 18； septin-associated RhoGEF； G蛋白偶联受体ARHGEF18；


背景信息：
Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). p114RgoGEF cts as guanine nucleotide exchange factor (GEF) for RhoA GTPases. It may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It also act as a GEF for RAC1, inducing production of reactive oxygen species (ROS), but does not act as a GEF for CDC42. The G protein beta-gamma (Gbetagamma) subunits of heterotrimeric G proteins act as activators, explaining the integrated effects of LPA and other G-protein coupled receptor agonists on actin stress fiber formation, cell shape change and ROS production.

宿主：Rbt
类型：Pab
同种型:IgG  
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user           
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。