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神经细胞鸟苷酸置换因子Ephexin1抗体
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
神经细胞鸟苷酸置换因子NGEF抗体
Anti-NGEF
产品介绍
靶标:

NGEF


产品别名:

ARHGEF27; EPHEXIN; NGEF; neuronal guanine nucleotide exchange factor; neuronal guanine nucleotide exchange factor; ephexin-1; eph-interacting exchange protein; ephexin1; 神经细胞鸟苷酸置换因子Ephexin1; 神经细胞鸟苷酸置换因子NGEF;


背景信息:
Acts as a guanine nucleotide exchange factor (GEF which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity.

宿主:Rbt
类型:Pab
同种型:IgG  
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user           
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。