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p53凋亡相关作用蛋白PMP22抗体
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
Anti-Perp
Anti-PERP, TP53 apoptosis effector Antibody
产品介绍
靶标:

Perp


产品别名:

1110017A08Rik; KCP1; KRTCAP1; PIGPC1; THW; Perp; PERP, TP53 apoptosis effector; PERP, TP53 apoptosis effector; p53 apoptosis effector related to PMP-22; KCP-1; keratinocyte-associated protein 1; p53 apoptosis effector related to Pmp22; p53 apoptosis-associated target; p53凋亡相关作用蛋白PMP22;


背景信息:
The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in the p53 network, including Chk2, p53R2, p53AIP1, Noxa, PIDD, PID/MTA2, MTBP and PERP, were identified and their genes were cloned recently. PERP, also termed PIGPC1 and THW, is a plasma membrane protein. p53 binds to the promoter of PERP and transcriptionally activates PERP gene then the translated PERP protein mediates the p53 induced apoptosis. The expression of PERP causes cell death. PERP is a mediator of p53 induced apoptosis. PERP has sequence similarity to PMP-22/gas3 and is a new member of the PMP-22/gas3 family.

宿主:Rbt
类型:Pab
同种型:IgG  
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user           
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。