E3连接酶MMS21蛋白抗体

立即咨询

E3连接酶MMS21蛋白抗体

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称

Anti-Nsmce2
Anti-NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase Antibody

产品介绍

靶标：

Nsmce2

产品别名：

1110014D18Rik； AI661537； Nsmce2； NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase； NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase； E3 SUMO-protein ligase NSE2； E3 SUMO-protein transferase NSE2； MMS21 homolog； non-SMC element 2 homolog (MMS21, S. cerevisiae)； non-structural maintenance of chromosomes element 2 homolog； E3连接酶MMS21蛋白；

背景信息：

NSMCE2 is the E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. NSMCE2 acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair.

宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。