环指蛋白34抗体

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环指蛋白34抗体

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称

Anti-RNF34
Anti-ring finger protein 34 Antibody

产品介绍

靶标：

RNF34

产品别名：

CARP-1； CARP1； RFI； RIF； RIFF； hRFI； RNF34； ring finger protein 34； ring finger protein 34； E3 ubiquitin-protein ligase RNF34； FYVE-RING finger protein MOMO； RING finger protein RIFF； RING-type E3 ubiquitin transferase RNF34； caspase regulator CARP1； caspases-8 and -10-associated RING finger protein 1； human RING finger homologous to inhibitor of apoptosis protein； ring finger protein 34, E3 ubiquitin protein ligase；环指蛋白34；

背景信息：

The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms.

宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。