L-796568, is a β3 adrenergic receptor agonist potentially for the treatment of obesity. L-796568 is a potent full beta(3) agonist (EC(50) = 3.6 nM, 94% activation) with >600-fold selectivity over the human beta(1) and beta(2) receptors, which also exhibits good orally bioavailable bioavailability in several mammalian species, as well as an extended duration of action. References: Dow RL, Paight ES, Schneider SR, Hadcock JR, Hargrove DM, Martin KA, Maurer TS, Nardone NA, Tess DA, DaSilva-Jardine P. Potent and selective, sulfamide-based human beta 3-adrenergic receptor agonists. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3235-40. PubMed PMID: 15149682.
纯度:≥98%
CAS:211031-81-1