ATP11A抗体

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ATP11A抗体

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称

Anti-ATP11A
Anti-ATPase phospholipid transporting 11A Antibody

产品介绍

靶标：

ATP11A

产品别名：

ATPIH； ATPIS； DFNA84； HLD24； ATP11A； ATPase phospholipid transporting 11A； ATPase phospholipid transporting 11A； phospholipid-transporting ATPase IH； ATPase, class VI, type 11A； P4-ATPase flippase complex alpha subunit ATP11A； phospholipid-translocating ATPase； potential phospholipid-transporting ATPase IH； probable phospholipid-transporting ATPase IH；

背景信息：

ATP11A is a widely expressed integral membrane ATPase. ATP11A is probably phosphorylated in its intermediate state and likely drives the transport of ions such as calcium or other molecules across membranes. While the exact molecule ATP11A transports is unknown, increased expression of ATP11A mRNA has been observed in murine leukemia cells made resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs). Furthermore, overexpression of ATP11A provided protection against the FTI SCH66336 while knockdown of ATP11A via siRNA made cells more sensitive to this drug. Other reports suggest that elevated levels of ATP11A mRNA may also be a predictive marker of metastasis in colorectal cancer patients.

宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。