靶标:
Ilp2
产品别名:
CG8167; DILP; DILP 2; DILP-2; DILP2; Dilp; Dilp 2; Dilp-2; Dilp2; Dmel\CG8167; ILP2; IRP; Ilp; Ilp-2; dILP-2; dILP2; dIlp2; dilp; dilp-2; dilp2; dipl2; ilp2; Ilp2; Insulin-like peptide 2; Insulin-like peptide 2; Insulin-like peptide 2; CG8167-PA; Dilp2; Ilp2-PA; Insulin- related peptide 2; Insulin-like peptide; Insulin-related peptide; drosophila insulin like peptide 2; drosophila insulin-like peptide 2; drosophila insulin-like receptor; insulin-like 2; insulin-like peptide-2;
背景信息:
Protects against apoptosis mediated by BAX.Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family including IAP, XIAP ILP-1 MIHA, and Livin KIAP that bind to and inhibits specific proteases. A novel member in the IAP protein family was recently identified and designated ILP-2 for IAP-like protein-2 (1). ILP-2 has high homology to ILP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues (1). ILP-2, unlike ILP-1, has no inhibitory effect on Fas and TNF induced apoptosis, but potently inhibits apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1. ILP-2 interacts with the processed caspase-9. These results suggest that ILP-2 is a novel IAP family member with restricted specificity for caspase-9.
宿主:Rbt
类型:Pab
同种型:IgG
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。