Salvinorin A is a potent, non-nitrogenous κ opioid selective receptor agonist. Salvinorin A is extracted from Salvia divinorum. Salvinorin A preserves cerebral pial artery autoregulation after forebrain ischemia via the PI3K/AKT/cGMP pathway. Salvinorin A ameliorates cerebral vasospasm through activation of endothelial nitric oxide synthase in a rat model of subarachnoid hemorrhage. References: Kivell BM, Paton KF, Kumar N, Morani AS, Culverhouse A, Shepherd A, Welsh SA, Biggerstaff A, Crowley RS, Prisinzano TE. Kappa Opioid Receptor Agonist Mesyl Sal B Attenuates Behavioral Sensitization to Cocaine with Fewer Aversive Side-Effects than Salvinorin A in Rodents. Molecules. 2018 Oct 11;23(10). pii: E2602. doi: 10.3390/molecules23102602. PubMed PMID: 30314288; PubMed Central PMCID: PMC6222496.

纯度：≥98%

CAS：83729-01-5