Saridegib HCl, formerly known as IPI-926 HCl, is a hedgehog pathway inhibitor which inhibits smoothened. References: Neelakantan D, Zhou H, Oliphant MUJ, Zhang X, Simon LM, Henke DM, Shaw CA, Wu MF, Hilsenbeck SG, White LD, Lewis MT, Ford HL. EMT cells increase breast cancer metastasis via paracrine GLI activation in neighbouring tumour cells. Nat Commun. 2017 Jun 12;8:15773. doi: 10.1038/ncomms15773. Erratum in: Nat Commun. 2018 Nov 12;9(1):4720. PubMed PMID: 28604738; PubMed Central PMCID: PMC5472791.
纯度:≥98%
CAS:1169829-40-6