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PI-3065
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PI-3065图片
CAS NO:955977-50-1
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品名称
PI3065, PI 3065
产品介绍

生物活性

PI-3065是p110δ激酶的小分子和选择性抑制剂,Ki值为1.5nM,IC50值为5nM。

Targets

TargetValue
p110δIC50: 15nM
p110βIC50: 1078nM
p110αIC50: 2299nM
mTORIC50: 9082nM
DNA-PKIC50: >10000nM
p110γIC50: 27542nM

化学数据

目录号A14338
作用机制Inhibitor (抑制剂)
M. Wt506.64
FormulaC27H31FN6OS
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.955977-50-1
SynonymsPI3065, PI 3065
SMILESC1CC1CN2CCN(CC2)CC3=CC4=C(S3)C(=NC(=N4)C5=C(C=CC6=C5C=CN6)F)N7CCOCC7

溶解度

In vitroDMSOWarmed: 50 mg/mL (98.68 mM)
WaterInsoluble
EthanolInsoluble
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM19.74 mL98.69 mL197.38 mL
0.5 mM3.95 mL19.74 mL39.48 mL
1 mM1.97 mL9.87 mL19.74 mL
5 mM0.39 mL1.97 mL3.95 mL

*The above data is based on the productmolecular weight 506.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.