TX1-85-1 (TX1851) is a novel and potent ErbB3 (HER3) inhibitor (IC50 = 23 nM) with anticancer activity. It exerts Her3-dependent pharmacology through an allosteric mechanismthereby disrupting interactions between Her3 and other proteins such as Her3 or cMet consistent with results presented here and distinct from conventional kinase inhibitors, which block catalytic function.

纯度：≥98%

CAS：1603845-32-4