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重组周期素D相关蛋白
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
Recombinant RUNX1T1
Recombinant RUNX1 partner transcriptional co-repressor 1 protein
产品介绍
基因名:

RUNX1T1


产品别名:

AML1-MTG8; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2; RUNX1T1; RUNX1 partner transcriptional co-repressor 1; RUNX1 partner transcriptional co-repressor 1; protein CBFA2T1; RUNX1 translocation partner 1; acute myelogenous leukemia 1 translocation 1, cyclin-D related; core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related; eight twenty one protein; myeloid translocation gene on 8q22; runt related transcription factor 1; translocated to, 1 (cyclin D related); zinc finger MYND domain-containing protein 2; 周期素D相关蛋白;


背景信息:
RUNX1T1 is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Several transcript variants encoding multiple isoforms have been found for this gene.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。