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重组细胞色素cP4501B1蛋白
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称
重组细胞色素P450家族成员1B1(CYP1B1)蛋白
Recombinant CYP1B1
产品介绍
基因名：

CYP1B1


产品别名：

ASGD6； CP1B； CYPIB1； GLC3A； P4501B1； CYP1B1； cytochrome P450 family 1 subfamily B member 1； cytochrome P450 family 1 subfamily B member 1； cytochrome P450 1B1； aryl hydrocarbon hydroxylase； cytochrome P450, family 1, subfamily B, polypeptide 1； cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile)； dioxin-inducible cytochrome p450； flavoprotein-linked monooxygenase； hydroperoxy icosatetraenoate dehydratase； microsomal monooxygenase； xenobiotic monooxygenase； 细胞色素cP4501B1； 细胞色素P450家族成员1B1(CYP1B1)；


背景信息：
Cytochrome P450 1B1 is a key enzyme involved in the production of potentially carcinogenic estrogen metabolites and the activation of environmental carcinogens and is the predominant member of the CYP1 family expressed in normal breast tissue and breast cancer. Estrogen has been proposed to trigger breast cancer development via an initiating mechanism involving its metabolite, catechol estrogen (CE). CYP1B1 catalyzes the conversion of 17-beta-estradiol to the catechol estrogen metabolites 2-OH-E2 and 4-OH-E2 which have both been postulated to be involved in mammary carcinogenesis.
Genetic polymorphisms in CYP1B1 may play an important role in human prostate carcinogenesis as well. Polymorphism of the CYP1B1 gene at codon 432 (Val-->Leu) is associated with a change in catalytic function.

标签：His-tag   
分类：Recombinant  
类型：Protein   
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。