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重组免疫球蛋白μ链结合蛋白2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
Recombinant IGHMBP2
Recombinant immunoglobulin mu DNA binding protein 2 protein
产品介绍
基因名:

IGHMBP2


产品别名:

CATF1; CMT2S; HCSA; HMN6; SMARD1; SMUBP2; ZFAND7; IGHMBP2; immunoglobulin mu DNA binding protein 2; immunoglobulin mu DNA binding protein 2; DNA-binding protein SMUBP-2; ATP-dependent helicase IGHMBP2; GF-1; cardiac transcription factor 1; glial factor 1; immunoglobulin mu binding protein 2; zinc finger, AN1-type domain 7; 免疫球蛋白μ链结合蛋白2;


背景信息:
IGHMBP2 is a 993 amino acid nuclear and cytoplasmic protein that is ubiquitously expressed. Belonging to the DNA2/NAM7 helicase family, IGHMBP2 is a 5' to 3' helicase that unwinds RNA and DNA duplexes in an ATP-dependent reaction. IGHMBP2 also acts as a transcriptional regulator and is necessary for transcriptional activation of the flounder liver-type antifreeze protein gene. IGHMBP2 exists as a homooligomer and is part of the cytosolic ribonucleoprotein complex. Mutations in the gene encoding IGHMBP2 are suggested to lead to distal hereditary motor neuronopathy type 6 (HMN6), also known as spinal muscular atrophy distal autosomal recessive 1 (DSMA1) or spinal muscular atrophy with respiratory distress 1 (SMARD1). HMN6 is characterized by weakness and wasting of distal muscles of the anterior tibial and peroneal compartments of the legs and severe respiratory distress.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。