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重组Bcl2相关髓细胞白血病序列1(MCL1)蛋白
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
重组磷酸化髓样细胞白血病-1蛋白
Recombinant MCL1
产品介绍
基因名:

MCL1


产品别名:

BCL2L3; EAT; MCL1-ES; MCL1L; MCL1S; Mcl-1; TM; bcl2-L-3; mcl1/EAT; MCL1; MCL1 apoptosis regulator, BCL2 family member; MCL1 apoptosis regulator, BCL2 family member; induced myeloid leukemia cell differentiation protein Mcl-1; BCL2 family apoptosis regulator; MCL1, BCL2 family apoptosis regulator; bcl-2-like protein 3; bcl-2-related protein EAT/mcl1; myeloid cell leukemia 1; myeloid cell leukemia ES; myeloid cell leukemia sequence 1 (BCL2-related); Bcl2相关髓细胞白血病序列1(MCL1); 磷酸化髓样细胞白血病-1; 磷酸化髓样细胞白血病1; 髓样细胞白血病-1;


背景信息:
Mcl1 is an anti-apoptotic member of Bcl2 family originally isolated from the ML1 human myeloid leukemia cell line during phorbol ester-induced differentiation along the monocyte/macrophage pathway. Mcl1 localizes to the mitochondria, interacts with and antagonizes pro-apoptotic Bcl2 family members, and inhibits apoptosis by a number of cytotoxic stimuli. It is involved in programing of differentiation and concomitant maintenance of viability but not of proliferation. Isoform 1 inhibits apoptosis while isoform 2 promotes it. Expression increases early during phorbol-ester induced differentiation along the monocyte/macrophage pathway in myeloid leukemia cell lines ML1.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。