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重组ATP依赖解旋酶SMARCA2蛋白
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称
Recombinant SMARCA2
Recombinant SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 protein
产品介绍
基因名：

SMARCA2


产品别名：

BAF190； BIS； BRM； NCBRS； SNF2； SNF2L2； SNF2LA； SWI2； Sth1p； hBRM； hSNF2a； SMARCA2； SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2； SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2； probable global transcription activator SNF2L2； ATP-dependent helicase SMARCA2； BAF190B； BRG1-associated factor 190B； SNF2-alpha； SNF2/SWI2-like protein 2； SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2； brahma homolog； global transcription activator homologous sequence； protein brahma homolog； putative global transcription activator SNF2L2； sucrose nonfermenting 2-like protein 2； ATP依赖解旋酶SMARCA2；


背景信息：
A transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. SMARCA2 / BRM belongs to the SNF2/RAD54 helicase family, is a homologue of the Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma proteins. It contains a methyl lysine containing bromo domain and an HSA domain. The yeast protein SNF2, also known as SWI2, is involved in transcriptional activation of numerous genes. It contains a domain that is highly conserved among several known helicases and is required for transcriptional activity. SNF2/SWI2 is highly homologous to the Drosophila protein 'brahma' (brm). Although the 2 proteins show nuclear localization during interphase, they are excluded from the condensed chromosomes during mitosis. They found that the level of BRM, but not BRG1, was strongly reduced during mitosis. Phosphorylation of hbrm and BRG1 did not disrupt their association with SNF5 but correlated with a decreased affinity for the nuclear structure in early M phase.

标签：His-tag   
分类：Recombinant  
类型：Protein   
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。