基因名：
PPM1F
产品别名：
CAMKP； CaMKPase； FEM-2； POPX2； hFEM-2； PPM1F； protein phosphatase, Mg2+/Mn2+ dependent 1F； protein phosphatase, Mg2+/Mn2+ dependent 1F； protein phosphatase 1F； Ca(2+)/calmodulin-dependent protein kinase phosphatase； CaM-kinase phosphatase； PP2C phosphatase； partner of PIX 2； protein fem-2 homolog； protein phosphatase 1F (PP2C domain containing)； 钙调蛋白依赖性蛋白激酶磷酸酶；
背景信息：
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined. [provided by RefSeq, Jul 2008].
标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
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