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重组鸟嘌呤核苷酸交换因子FARP2蛋白
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称
Recombinant FARP2
Recombinant FERM, ARH/RhoGEF and pleckstrin domain protein 2 protein
产品介绍
基因名：

FARP2


产品别名：

FIR； FRG； PLEKHC3； FARP2； FERM, ARH/RhoGEF and pleckstrin domain protein 2； FERM, ARH/RhoGEF and pleckstrin domain protein 2； FERM, ARHGEF and pleckstrin domain-containing protein 2； FERM domain including RhoGEF； FERM, RhoGEF and pleckstrin domain protein 2； FERM, RhoGEF and pleckstrin domain-containing protein 2； FGD1-related Cdc42-GEF； PH domain-containing family C member 3； pleckstrin homology domain-containing family C member 3； 鸟嘌呤核苷酸交换因子FARP2；


背景信息：
FARP2 is a 1,545 amino acid protein that contains one FERM domain, one DH domain and two PH domains. It exists as two alternatively spliced isoforms that are abundantly expressed in brain, lung, and testis as well as in embryonic hippocampal and cortical neurons. FARP2 functions as a Rho-guanine nucleotide exchange factor that activates RAC1 and is thought to regulate neurite remodeling of embryonic neurons. Sema3A binding to neuropilin-1 induces the dissociation of FARP2 from plexin-A1, thereby activating FARP2's Rac GEF activity which is critical for repulsion of outgrowing axons and suppression of neuronal adhesion. Downregulation of the FARP2 gene has been implicated in autism.

标签：His-tag   
分类：Recombinant  
类型：Protein   
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。