基因名：
OLIG2
产品别名：
BHLHB1； OLIGO2； PRKCBP2； RACK17； bHLHe19； OLIG2； oligodendrocyte transcription factor 2； oligodendrocyte transcription factor 2； oligodendrocyte transcription factor 2； basic domain, helix-loop-helix protein, class B, 1； class B basic helix-loop-helix protein 1； class E basic helix-loop-helix protein 19； human protein kinase C-binding protein RACK17； oligodendrocyte lineage transcription factor 2； oligodendrocyte-specific bHLH transcription factor 2； protein kinase C-binding protein 2； 少突胶质细胞系转录因子2(OLIG2)； 磷酸化蛋白激酶C结合蛋白2；
背景信息：
The oligodendrocyte lineage-specific basic helix-loop-helix (OLIG) family of transcription factors include OLIG1-OLIG3, which differ in tissue expression. OLIG1 and OLIG2 are specifically expressed in nervous tissue as gene regulators of oligodendrogenesis. OLIG2 is more widely expressed in embryonic brain than OLIG1, while OLIG3 is primarily expressed in non-neural tissues. OLIG1 and OLIG2 interact with the Nkx-2.2 homeodomain protein, which is responsible for directing ventral neuronal patterning in response to graded Sonic hedgehog signaling in the embryonic neural tube. These interactions between OLIG proteins and Nkx-2.2 appear to promote the formation of alternate cell types by inhibiting V3 interneuron development. OLIG1 and OLIG2 are abundantly expressed in oligodendroglioma and nearly absent in astrocytomas. Therefore, OLIG proteins are candidates for molecular markers of human glial brain tumors, which are the most common primary malignancies of the human brain.
标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
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