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位置：首页 > 产品库 > 重组丝裂原激活蛋白激酶激酶激酶7相互作用蛋白1(MAP3K7IP1)
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重组丝裂原激活蛋白激酶激酶激酶7相互作用蛋白1(MAP3K7IP1)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称
重组磷酸化转化生长因子β活化激酶结合蛋白1
Recombinant TAB1
产品介绍
基因名：

TAB1


产品别名：

3'-Tab1； MAP3K7IP1； TAB1； TGF-beta activated kinase 1 (MAP3K7) binding protein 1； TGF-beta activated kinase 1 (MAP3K7) binding protein 1； TGF-beta-activated kinase 1 and MAP3K7-binding protein 1； TAK1-binding protein 1； mitogen-activated protein kinase kinase kinase 7-interacting protein 1； transforming growth factor beta-activated kinase-binding protein 1； 丝裂原激活蛋白激酶激酶激酶7相互作用蛋白1(MAP3K7IP1)； 磷酸化转化生长因子β活化激酶结合蛋白1； 转化生长因子β活化激酶结合蛋白1；


背景信息：
TAB1 was identified as a regulator of the MAP kinase kinase kinase TAK1/MAP3K7, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta and members of the Toll IL 1R (TIR) superfamily, thus acting as an intermediate in both proliferative and innate and adaptive immune responses. This protein, together with either TAB2 or TAB3, activates TAK1 kinase in response to upstream signals. It has been shown that the C terminal portion of TAB1 is sufficient for binding and activation of TAK1, while a portion of the N terminus acts as a dominant negative inhibitor of TGF beta, demonstrating how this protein can function as a mediator between TGF beta receptors and TAK1.

标签：His-tag   
分类：Recombinant  
类型：Protein   
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。