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重组早期B-细胞因子2(EBF2)蛋白
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
重组早期B淋巴细胞因子2蛋白
Recombinant Ebf2
产品介绍
基因名:

Ebf2


产品别名:

D14Ggc1e; EBF-2; Mmot1; O/E-3; OE-3; Ebf2; early B cell factor 2; early B cell factor 2; transcription factor COE2; MET-mesencephalon-olfactory TF1; MET-mesencephalon-olfactory transcription factor 1; Olf-1/EBF-like 3; metencephalon-mesencephalon-olfactory transcription factor 1; 早期B-细胞因子2(EBF2); 早期B淋巴细胞因子2;


背景信息:
Early B-cell factor 2 is a 575 amino acid protein belonging to the COE family of proteins, whose members are all helix-loop-helix transcription factors. EBF2 is a transcription factor which, in synergy with the Wnt-responsive LEF1/CTNNB1 pathway, activates the decoy receptor for RANKL, OPG, in osteoblasts. OPG, in turn, regulates osteoclast differentiation. Lack of EBF2 has been found to cause a small defect in the terminal differentiation of osteoblasts, along with reduced bone mass and an increase in osteoclasts. Localized to the nucleus, EBF2 forms a homodimer or a heterodimer with a related family member.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。