重组SARM蛋白

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重组SARM蛋白

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称

Recombinant SARM1
Recombinant sterile alpha and TIR motif containing 1 protein

产品介绍

基因名：

SARM1

产品别名：

HsTIR； MyD88-5； SAMD2； SARM； hSARM1； SARM1； sterile alpha and TIR motif containing 1； sterile alpha and TIR motif containing 1； NAD(+) hydrolase SARM1； NADP(+) hydrolase SARM1； NADase SARM1； SAM domain-containing protein 2； sterile alpha and Armadillo repeat protein； sterile alpha and HEAT/Armadillo motif protein, ortholog of Drosophila； sterile alpha and TIR motif-containing protein 1； sterile alpha motif domain-containing protein 2； tir-1 homolog； SARM蛋白；

背景信息：

SARM, also known as SAMD2, SARM1 or KIAA0524, is a 724 amino acid protein that localizes to the cytoplasm and contains one TIR domain and two sterile alpha motif (SAM) domains. Expressed predominately in liver and kidney and present at lower levels in placenta, SARM interacts with TICAM-1 and, via this interaction, blocks the transcriptional activation activity of TICAM-1 and functions as a negative regulator of Toll-like receptor signaling. Additionally, SARM is thought to be involved in innate immune responses and may also play a role in the negative regulation of NFⅹB activation. SARM exists as two alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 17.

标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。