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重组泛素连接酶NEDD4-2蛋白
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
重组磷酸化泛素连接酶NEDD4-2蛋白
Recombinant NEDD4L
产品介绍
基因名:

NEDD4L


产品别名:

NEDD4-2; NEDD4.2; PVNH7; RSP5; hNEDD4-2; NEDD4L; NEDD4 like E3 ubiquitin protein ligase; NEDD4 like E3 ubiquitin protein ligase; E3 ubiquitin-protein ligase NEDD4-like; HECT-type E3 ubiquitin transferase NED4L; neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase; ubiquitin-protein ligase Rsp5; 泛素连接酶NEDD4-2; 磷酸化泛素连接酶NEDD4-2;


背景信息:
This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。