重组LILRA4蛋白

立即咨询

重组LILRA4蛋白

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称

Recombinant LILRA4
Recombinant leukocyte immunoglobulin like receptor A4 protein

产品介绍

基因名：

LILRA4

产品别名：

CD85g； ILT7； LILRA4； leukocyte immunoglobulin like receptor A4； leukocyte immunoglobulin like receptor A4； leukocyte immunoglobulin-like receptor subfamily A member 4； CD85 antigen-like family member G； immunoglobulin-like transcript 7； leucocyte Ig-like receptor A4； leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4； leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 4；

背景信息：

LILRA4, also known as ILT7 and CD85g, is an approximately 60-70 kDa variably glycosylated transmembrane protein that regulates immune cell activation. Mature human LILRA4 consists of a 423 amino acid (aa) extracellular domain (ECD) with four immunoglobulin-like domains, a 21 aa transmembrane segment, and a 32 aa cytoplasmic domain.LILRA4 function coreceptor to limit the innate immune responses to viral infections; signaling occurs via FCER1G (PubMed:16735691, PubMed:19564354). Down-regulates the production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides, indicating it functions as negative regulator of TLR7 and TLR9 signaling cascades.

标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。