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重组细胞死亡调节蛋白(凋亡,半胱胺酸蛋白酶激活抑制剂)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
Recombinant Aven
Recombinant Apoptosis and caspase activation inhibitor protein
产品介绍
基因名:

Aven


产品别名:

CG15727; Dmel\CG15727; dAven; Aven; Apoptosis and caspase activation inhibitor; Apoptosis and caspase activation inhibitor; apoptosis and caspase activation inhibitor; Aven-PA; Aven-PB; CG15727-PA; CG15727-PB; aven ortholog; 细胞死亡调节蛋白(凋亡、半胱胺酸蛋白酶激活抑制剂);


背景信息:
Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. AVEN is a recently discovered protein that blocks apoptosis induced by Apaf-1 and caspase-9. It is thought that AVEN functions by binding to Bcl-xL, an antiapoptotic member of the Bcl-2 family, and to Apaf-1, possibly interfering with the ability of Apaf-1 to self-associate, suggesting that AVEN impedes Apaf-1-mediated caspase activation. Higher levels of AVEN mRNA are seen in patients with acute leukemia than in control patients, suggesting that AVEN may be useful as a prognostic indicator in leukemia patients.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。