重组Tuberin样蛋白1

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重组Tuberin样蛋白1

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称

Recombinant Ralgapa1
Recombinant Ral GTPase activating protein, alpha subunit 1 protein

产品介绍

基因名：

Ralgapa1

产品别名：

2310003F20Rik； 4930400K19Rik； AI563624； GRIPE； Garnl1； Tulip1； mKIAA0884； Ralgapa1； Ral GTPase activating protein, alpha subunit 1； Ral GTPase activating protein, alpha subunit 1； ral GTPase-activating protein subunit alpha-1； GAP-related interacting partner to E12； GTPase activating RANGAP domain-like 1； GTPase-activating RapGAP domain-like 1； p240； ral GTPase-activating protein alpha subunit 1； tuberin-like protein 1； tulip 1 protein； Tuberin样蛋白1；

背景信息：

GARNL1 is expressed during embryogenesis with E12. During development, GARNL1 expression decreases, persisting at high levels only in neurons of the adult brain. GARNL1 localizes to the cytoplasm where it may play a role regulating GTP hydrolysis of proteins such as Ran and Rap. GARNL1 is imported to the nucleus via dimerization with E12. GARNL1 interacts with the HLH region of E12 and may function to negatively regulate the transcription of E12-dependent downstream target genes. This suggests that at least a portion of the function of GARNL1 is dependent upon its association with E12. GARNL1 may also associate with other HLH proteins and influence a variety of HLH signaling cascades. In adult brain, GARNL1 activity does not involve E12 and therefore it may serve a different function in developed neural tissue.

标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。