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重组G蛋白偶联受体109A
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
Recombinant Hcar2
Recombinant hydroxycarboxylic acid receptor 2 protein
产品介绍
基因名:

Hcar2


产品别名:

Gpr109a; Gpr109b; HM74; Niacr1; PUMA-G; Pumag; mHM74b; Hcar2; hydroxycarboxylic acid receptor 2; hydroxycarboxylic acid receptor 2; hydroxycarboxylic acid receptor 2; G protein-coupled receptor 109A; G protein-coupled receptor 109B; G-protein coupled receptor 109; G-protein coupled receptor HM74; interferon-gamma inducible gene, Puma-g; niacin receptor 1; nicotinic acid receptor; putative seven transmembrane spanning receptor; G蛋白偶联受体109A;


背景信息:
Acts as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G(i)-protein-mediated inhibition of adenylyl cyclase. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. Mediates nicotinic acid-induced apoptosis in mature neutrophils. Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity of cAMP-dependent protein kinase A and phosphorylation of target proteins, leading to neutrophil apoptosis.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。