PGP-4008 is a selective inhibitor of P-glycoprotein (P-gp) that does not affect the activity of multidrug resistance-related protein 1 (MRP1). PGP-4008, in combination with doxorubicin showed inhibition of tumor growth. References: Huang L, Wang J, Chen WC, Li HY, Liu JS, Tao Jiang, Yang WD. P-glycoprotein expression in Perna viridis after exposure to Prorocentrum lima, a dinoflagellate producing DSP toxins. Fish Shellfish Immunol. 2014 Aug;39(2):254-62. doi: 10.1016/j.fsi.2014.04.020. PubMed PMID: 24811006.
纯度:≥98%
CAS:365565-02-2