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Nitromifene Citrate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:5863-35-4
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

Nitromifene Citrate A non-steroidal estrogen antagonist (as 1 citrate) most commonly used as a research tool in animal studies. References: Henley CL, Nunez AA, Clemens LG. Hormones of choice: the neuroendocrinology of partner preference in animals. Front Neuroendocrinol. 2011 Apr;32(2):146-54. doi: 10.1016/j.yfrne.2011.02.010. Epub 2011 Mar 4. Review. PubMed PMID: 21377487. 2: Nakamura NH, McEwen BS. Changes in interneuronal phenotypes regulated by estradiol in the adult rat hippocampus: a potential role for neuropeptide Y. Neuroscience. 2005;136(1):357-69. Epub 2005 Sep 28. PubMed PMID: 16198490. 3: Rudick CN, Woolley CS. Selective estrogen receptor modulators regulate phasic activation of hippocampal CA1 pyramidal cells by estrogen. Endocrinology. 2003 Jan;144(1):179-87. PubMed PMID: 12488344. 4: Young EA, Altemus M, Parkison V, Shastry S. Effects of estrogen antagonists and agonists on the ACTH response to restraint stress in female rats. Neuropsychopharmacology. 2001 Dec;25(6):881-91. PubMed PMID: 11750181. 5: McEwen BS, Tanapat P, Weiland NG. Inhibition of dendritic spine induction on hippocampal CA1 pyramidal neurons by a nonsteroidal estrogen antagonist in female rats. Endocrinology. 1999 Mar;140(3):1044-7. PubMed PMID: 10067823. 6: Kisley LR, Sakai RR, Ma LY, Fluharty SJ. Ovarian steroid regulation of angiotensin II-induced water intake in the rat. Am J Physiol. 1999 Jan;276(1 Pt 2):R90-6. PubMed PMID: 9887181. 7: Vega Matuszczyk J, Appa RS, Larsson K. Postnatal testicular secretions partially restore the disturbances in reproductive activity caused by prenatal hormonal manipulation. Physiol Behav. 1997 Jul;62(1):137-43. PubMed PMID: 9226353. 8: Vega Matuszczyk JV, Larsson K. Sexual preference and feminine and masculine sexual behavior of male rats prenatally exposed to antiandrogen or antiestrogen. Horm Behav. 1995 Jun;29(2):191-206. PubMed PMID: 7557922. 9: Sayag N, Snapir N, Arnon E, el Halawani ME, Grimm VE, Robinzon B. Sexual differentiation of copulatory behaviour in the male chick requires gonadal steroids. Br Poult Sci. 1991 Jul;32(3):607-17. PubMed PMID: 1893270. 10: Schlinger BA, Callard GV. Aromatization mediates aggressive behavior in quail. Gen Comp Endocrinol. 1990 Jul;79(1):39-53. PubMed PMID: 2191894. 1 Huet-Hudson YM, Dey SK. Differential effects of ovarian steroids and triphenylethylene compounds on macromolecular uptake and thymidine incorporation in the mouse uterus. J Steroid Biochem. 1990 Jan;35(1):23-7. PubMed PMID: 2407900. 12: Ruenitz PC, Thompson CB, Srivatsan V. Characterization of MCF 7 breast cancer cell growth inhibition by the antiestrogen nitromifene (CI 628) and selected metabolites. J Steroid Biochem. 1989 Sep;33(3):365-9. PubMed PMID: 2550704. 13: Dumesic DA, Renk M, Kamel F. Estrogenic effects of phenol red on rat pituitary cell responsiveness to gonadotropin-releasing hormone. Life Sci. 1989;44(6):397-406. PubMed PMID: 2645497. 14: Fargin A, Faye JC, le Maire M, Bayard F, Potier M, Beauregard G. Solubilization of a tamoxifen-binding protein. Assessment of its molecular mass. Biochem J. 1988 Nov 15;256(1):229-36. PubMed PMID: 3066343; PubMed Central PMCID: PMC1135392. 15: Pasqualini JR, Sumida C, Giambiagi N. Pharmacodynamic and biological effects of anti-estrogens in different models. J Steroid Biochem. 1988 Oct;31(4B):613-43. Review. PubMed PMID: 3059059. 16: Huet YM, Dey SK. A paradoxical effect of an antiestrogen, CI-628, on implantation in the mouse. Proc Soc Exp Biol Med. 1988 Oct;189(1):61-5. PubMed PMID: 3054903. 17: Borgna JL, Scali J. Differential inhibition of estrogen and antiestrogen binding to the estrogen receptor by diethylpyrocarbonate. J Steroid Biochem. 1988 Oct;31(4A):427-36. PubMed PMID: 3050278. 18: Juriansz RL, Huseby RA, Wilcox RB. Interactions of putative estrogens with the intracellular receptor complex in mouse Leydig cells: relationship to preneoplastic hyperplasia. Cancer Res. 1988 Jan 1;48(1):14-8. PubMed PMID: 3334987. 19: Huet YM, Dey SK. Role of early and late oestrogenic effects on implantation in the mouse. J Reprod Fertil. 1987 Nov;81(2):453-8. PubMed PMID: 3323496. 20: Watts CK, Sutherland RL. Studies on the ligand specificity and potential identity of microsomal antiestrogen-binding sites. Mol Pharmacol. 1987 May;31(5):541-51. PubMed PMID: 3553893.

纯度:≥98%

CAS:5863-35-4