PMX-53 (3D53), a synthetic peptide, is a novel potent and orally bioactive dual C5aR(CD88) antagonist and Mas-related gene 2 (MrgX2) agonist. PMX-53 inhibits C5a-induced hypernociception in rats, inhibits lung metastasis in a mouse breast cancer model and reduces atherosclerotic lesions in a mouse model of atherosclerosis.
纯度:≥98%
CAS:219639-75-5