Description: Ifenprodil is a potent and atypical noncompetitive antagonist at the NMDA receptor, it interacts with high affinity at a homogeneous population of NMDA receptors in neonatal rat forebrain with IC50 of 0.3 μM. Ifenprodil inhibits NMDA-induced currents at NR1A/NR2B and NR1A/NR2A receptors with IC50 of 0.34 μM and 146 μM in oocytes voltage-clamped at -70 mV.
References: Mol Pharmacol. 1993 Oct;44(4):851-9; J Neurosci. 1998 Mar 15;18(6):1935-43.
Related CAS #: 23210-58-4 (tartrate); 23210-56-2 (free base); 66157-43-5 (tartrate); 66516-92-5 (Ifenprodil glucuronide)
纯度:≥98%
CAS:23210-56-2