iKIX1 is a novel and potent inhibitor of Pdr1-dependent gene activation with antifungal activity. It is able to resensitize drug-resistant C. glabrata to azole antifungals in vitro and in animal models for disseminated and urinary tract C. glabrata infection, also inhibits the interaction between the KIX domain of the mediator subunit CgGal11A and the activation domain of CgPdr1, the IC50 and Ki values are 190.2 μM and 18 μM, respectively.

纯度：≥98%

CAS：656222-54-7