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IDE1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
IDE1图片
CAS NO:1160927-48-9
规格:≥98%
包装与价格:
包装价格(元)
25mg电议
50mg电议
100mg电议
250mg电议
500mg电议

产品介绍

IDE1 (Inducer of definitive endoderm 1) is a novel, potent and cell-permeable inducer of definitive endoderm formation with EC50 of 125 nM). IDE1 induces Sox17 expression. It also activates TGF-β signaling and downstream Smad2 phosphorylation. IDE1 upregulates Nodal expression. It induces differentiation of mouse or human pluripotent stem cells (PSCs) by activating SMAD2 phosphorylation and NODAL expression (Borowiak et al.). At EC50 = 125 nM, SOX17 expression was induced in mouse ES cells.

纯度:≥98%

CAS:1160927-48-9