SPV106 is a novel ligand of lysine acetyltransferases (KATs), possessing a previously unobserved inhibitor/activator activity profile against protein acetyltransferases. References: Castellano S, Milite C, Feoli A, Viviano M, Mai A, Novellino E, Tosco A, Sbardella G. Identification of structural features of 2-alkylidene-1,3-dicarbonyl derivatives that induce inhibition and/or activation of histone acetyltransferases KAT3B/p300 and KAT2B/PCAF. ChemMedChem. 2015 Jan;10(1):144-57. doi: 10.1002/cmdc.201402371. Epub 2014 Oct 21. PubMed PMID: 25333655.
纯度:≥98%
CAS:1036939-38-4