Hepsulfam is a bisulfamic ester which is similar in structure to busulfan and belongs to the family of drugs known as alkylsulfonate alkylating agents. Hepsulfam forms covalent linkages with nucleophilic centers in DNA, resulting in depurination, base miscoding, strand scission, DNA-DNA and DNA-protein cross-linking, and cytotoxicity. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus) References: Je KH, Son JK, O'Connor TR, Lee CS. Hepsulfam induced DNA adducts and its excision repair by bacterial and mammalian 3-methyladenine DNA glycosylases. Mol Cells. 1998 Dec 31;8(6):691-7. PubMed PMID: 9895121.

纯度：≥98%

CAS：96892-57-8