HDAC6 degrader 9c, formerly known as dHDAC6 9c, is a bifunctional molecule that selectively degrades HDAC6 by conjugating a non-selective HDAC inhibitor to a thalidomide-type E3 ligase ligand. This process causes degradation of HDAC6 in a dose dependent manner and upregulation of acetylated α-tubulin. References: Yang K, Song Y, Xie H, Wu H, Wu YT, Leisten ED, Tang W. Development of the first small molecule histone deacetylase 6 (HDAC6) degraders. Bioorg Med Chem Lett. 2018 Aug 1;28(14):2493-2497. doi: 10.1016/j.bmcl.2018.05.057. Epub 2018 May 30. PubMed PMID: 29871848.

纯度：≥98%

CAS：2235382-05-3