GW-803430 is a potent, orally bioavailable and selective melanin-concentrating hormone receptor 1 (MCH1) antagonist (IC50 = 9.3 nM). GW-803430 exhibits antiobesity and antidepressant-like effects in rats and mice. References: Rabal O, Amr FI, Oyarzabal J. Novel Scaffold FingerPrint (SFP): applications in scaffold hopping and scaffold-based selection of diverse compounds. J Chem Inf Model. 2015 Jan 26;55(1):1-18. doi: 10.1021/ci500542e. Epub 2015 Jan 13. PubMed PMID: 25558803.

纯度：≥98%

CAS：515141-51-2