T-3861174 is a prolyl tRNA synthetase (PRS) inhibitor, exhibiting significant in vitro anti-tumor activity with GCN2-ATF4 pathway activation. References: Arita T, Morimoto M, Yamamoto Y, Miyashita H, Kitazawa S, Hirayama T, Sakamoto S, Miyamoto K, Adachi R, Iwatani M, Hara T. Prolyl-tRNA synthetase inhibition promotes cell death in SK-MEL-2 cells through GCN2-ATF4 pathway activation. Biochem Biophys Res Commun. 2017 Jul 8;488(4):648-654. doi: 10.1016/j.bbrc.2017.01.045. Epub 2017 Jan 11. PubMed PMID: 28087278.

纯度：≥98%

CAS：2209057-94-1