TAS-109, formerly known as DFP-10917 and CNDAC, is an analogue of the nucleoside deoxycytidine with potential antineoplastic activity. Nucleoside analogue TAS-109 is incorporated into DNA and directly inhibits the activity of DNA polymerase, which may result in inhibition of DNA replication and cell cycle arrest in the S and G2/M phases, DNA fragmentation, and tumor cell apoptosis. References: Reeves MD. Increase in quality, but not quantity, of clinical trials in acute pain: 1992 versus 2007. Anesth Analg. 2009 Nov;109(5):1656-8. PubMed PMID: 19843804.
纯度:≥98%
CAS:135598-68-4