Glibenclamide impurity A is an inhibitor of the formation of the NLRP3 inflammasome in cardiomyocytes. It acts by limiting the infarct size following myocardial ischemia/reperfusion in the mouse, without affecting glucose metabolism. References: Marchetti C, Chojnacki J, Toldo S, Mezzaroma E, Tranchida N, Rose SW, Federici M, Van Tassell BW, Zhang S, Abbate A. A novel pharmacologic inhibitor of the NLRP3 inflammasome limits myocardial injury after ischemia-reperfusion in the mouse. J Cardiovasc Pharmacol. 2014 Apr;63(4):316-322. doi: 10.1097/FJC.0000000000000053. PubMed PMID: 24336017; PubMed Central PMCID: PMC3980088.

纯度：≥98%

CAS：16673-34-0